The ongoing dispute regarding what constitutes adequate vitamin D levels in the medical field has led to conflicting recommendations and differing viewpoints. While the Institute of Medicine (IOM) proposed a 20 ng/mL threshold for optimal bone health, the Endocrine Society suggested higher levels, aiming for 30 ng/mL, with an optimal range of 40-60 ng/mL. Conversely, the New England Journal of Medicine argued for a significantly lower cutoff at 12.5 ng/mL, challenging the prevalence of deficiency. Dr. Joel Finkelstein, an eminent figure in osteoporosis research, supports the notion of potential over-screening and overtreatment, offering an intriguing evolutionary perspective. He questions the evolutionary rationale behind humans requiring a nutrient that is relatively scarce in natural sources, particularly when considering adaptive traits like darker skin that might hinder its absorption. This ongoing controversy highlights the complexity of determining precise vitamin D thresholds and emphasizes the necessity for continual research and nuanced approaches in medical practice.
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