Tissue Transglutaminase (TTG) IgG, IgA

The Tissue Transglutaminase (TTG) IgA, IgM, or IgG test is an integral component of the diagnostic process for celiac disease, an autoimmune disorder characterized by the immune system mistakenly perceiving gluten as a foreign invader. In individuals with celiac disease, antibodies are produced that target a specific enzyme called tissue transglutaminase (TTG) present in the intestines. This immune response results in damage to the intestinal lining, leading to various symptoms and potential long-term health complications. By identifying the presence of TTG antibodies in the blood using specialized IgA, IgM, or IgG tests, healthcare professionals can gain crucial insights into the likelihood of celiac disease, facilitating an accurate diagnosis and subsequent management of this condition, particularly in the context of Hypro Diagnostic.