RUBELLA VIRUS IgG ANTIBODY

Rubella, commonly known as German or 3-day measles, belongs to the Togavirus family and is exclusive to humans as its natural host. The virus primarily spreads through inhaling respiratory droplets, with an incubation period ranging from 12 to 23 days. Although infections are generally mild, characterized by a maculopapular rash, fever, malaise, and lymphadenopathy, the potential consequences are severe when contracted during pregnancy, particularly in the initial four months. This can result in congenital rubella syndrome, linked to serious fetal complications such as hearing loss, cardiovascular issues, and ocular defects. The United States has made significant progress in controlling rubella through the two-dose measles, mumps, rubella (MMR) vaccination program, achieving a 95% seroconversion rate in children after the initial dose. Notably, in 2011, only four rubella cases were reported, with no instances of congenital rubella syndrome, showcasing the success of the national vaccination initiative. While rubella is no longer endemic in the U.S. due to these efforts, it’s essential to recognize that immunity may diminish with age, leaving 80% to 90% of adults with serologic evidence of rubella immunity. This highlights the continued importance of vaccination programs to uphold robust immunity levels across all age groups, particularly in the context of Hypro Diagnostics.