HBe AB

Following recovery from acute hepatitis B, there is a distinctive shift in viral markers—HBeAg levels decrease, becoming undetectable, while anti-HBe appears in the serum and persists for years post-recovery. In chronic hepatitis B carriers, a positive anti-HBe typically signals viral inactivity and low infectivity. However, if anti-HBe is detected alongside measurable HBV DNA in the serum, it indicates active viral replication and ongoing infection. This nuanced interpretation of anti-HBe results is crucial for accurately assessing the status of individuals carrying the hepatitis B virus or those with chronic hepatitis B, distinguishing between viral inactivity and ongoing replication.