Coagulation Profile

A Coagulation Profile (PT/INR & aPTT) comprises two essential tests: the prothrombin time international normalized ratio (PT/INR) and the activated partial thromboplastin time (aPTT). These tests are instrumental in determining the concentration of coagulation factors—proteins in the blood responsible for facilitating clot formation to control bleeding. The assessment of coagulation ability through this profile is valuable for gauging the risk of excessive bleeding or the formation of blood clots (thrombosis). Coagulation factors, also referred to as clotting factors, are proteins within the blood plasma (the liquid component of blood) that play a crucial role in halting bleeding when there is a wound or cut. The coagulation process involves a cascade of reactions activated by these clotting factors. There are thirteen clotting factors in the body, working in harmony to ensure healthy clot formation. Maintaining the proper balance of these factors is essential, as any imbalance can lead to a blood clotting disorder. The Coagulation Profile is a valuable tool for assessing and monitoring these factors, providing insights into the clotting mechanism and helping diagnose potential clotting disorders.