BLOOD GROUPING AND RH FACTOR
The Rh blood group system, mistakenly named after the Rhesus monkey six decades ago, has evolved into a crucial element in transfusion medicine and obstetrics, standing second only to the ABO blood group. The complexity of Rh antigens stems from the intricate dance of highly polymorphic genes, predominantly RHD and RHCE, resulting in a staggering array of 49 recognized Rh antigens. Beyond its genetic maze, the Rh blood group’s significance lies in the remarkable immunogenicity of its antigens, notably the D antigen. Individuals lacking the D antigen may trigger an immune response against it, leading to potentially severe reactions in blood transfusions or the development of hemolytic disease in newborns. The physiological functions of Rh proteins remain veiled in speculation, suggesting involvement in ammonium transport and maintaining red blood cell membrane integrity. Deciphering these genetic and functional enigmas not only deepens our comprehension of human biology but also significantly influences medical practices, ensuring safer transfusions and improved outcomes in maternal and fetal health – a vital aspect for Hypro Diagnostics to consider in their diagnostic endeavors.
Reviews
There are no reviews yet.