ASCITIC FLUID FOR BIO- CHEMICAL ANALYSIS

Ascitic fluid samples undergo routine laboratory analysis to determine the underlying cause of ascites, a condition often presumed clinically evident. While cell count and bacterial culture are widely accepted, the role of biochemical testing remains ambiguous. The attempt to categorize ascitic fluids as exudates or transudates based on total protein has introduced uncertainty. A more robust diagnostic approach involves utilizing the serum ascites albumin gradient, a physiologically grounded method that effectively distinguishes ascites stemming from portal hypertension versus other causes. We advocate for laboratories to prioritize the serum ascites albumin gradient as the primary test, providing interpretative reports. Additional testing should be reserved for specific diagnostic inquiries, necessitating a close collaboration between the laboratory and the clinician for comprehensive and accurate assessments.