ANTI MICROSOMAL ANTI BODIES

Antimicrosomal antibodies, notably anti-TPO, are key players in autoimmune thyroid disorders. While normal levels typically hold minimal clinical significance, elevated concentrations are linked to conditions like Hashimoto thyroiditis, primary myxedema causing hypothyroidism, and Graves’ disease inducing hyperthyroidism. When thyroid function tests are abnormal, these antibodies signal potential glandular damage. In individuals with normal thyroid function, their presence hints at a possible risk of future thyroid issues, with higher levels correlating to an increased autoimmune thyroid risk. Additionally, pregnant women with these antibodies face heightened risks for thyroid problems in their babies. Beyond thyroid disorders, antimicrosomal antibodies are also associated with various autoimmune conditions like type 1 diabetes, pernicious anemia, rheumatoid arthritis, and systemic lupus erythematosus (SLE).