ANTI HEV IgG

Hepatitis E virus (HEV) usually leads to a self-limiting acute infection, transmitted from animal reservoirs like hogs to humans through the fecal-oral route. While endemic in Southeast and Central Asia, outbreaks occur in regions like the Middle East, Africa, and Mexico. Severe cases often affect young to middle-aged adults, with higher mortality rates, particularly among pregnant individuals in their third trimester. Unlike a carrier state, immunocompromised patients might experience extended periods of virus presence. In most cases, HEV prompts symptoms after an incubation period of 15 to 60 days, marked by anti-HEV IgM in serum followed by detectable anti-HEV IgG. Anti-HEV IgG, persisting for years, serves as the primary serologic marker for past HEV exposure.