ANTI DNA ANTIBODY -DS TITRE

Anti-DNA antibodies, specifically those directed against double-stranded (ds) DNA, are immune proteins linked to autoimmune disorders, particularly systemic lupus erythematosus (SLE). These antibodies erroneously target the body’s own genetic material, causing inflammation and tissue damage. The term “titre” in “anti-DNA antibody-DS titre” refers to the concentration of these antibodies in the blood, typically assessed through laboratory methods like enzyme-linked immunosorbent assay (ELISA) or immunofluorescence assays. The numerical result obtained from these tests signifies the level of anti-DNA antibodies against dsDNA. Monitoring the anti-DNA antibody titre is pivotal for both diagnosing and managing autoimmune diseases, offering valuable insights into disease activity and treatment response. Elevated titres may indicate ongoing autoimmune processes, while a decline in titres could suggest a positive response to therapy. Consistent monitoring of these antibody levels assists healthcare professionals in crafting personalized treatment plans for individuals with autoimmune conditions.