ADA- ADENOSINE DEAMINASE

Adenosine deaminase (ADA) stands as a vital enzyme within the purine metabolism pathway, facilitating the irreversible conversion of adenosine and deoxyadenosine into inosine and deoxyinosine, respectively. This enzymatic process plays a crucial role in maintaining the balance of purine nucleotides essential for cellular functions. By catalyzing this deamination reaction, ADA contributes significantly to regulating nucleotide levels, impacting cellular energy metabolism and various physiological processes. Its activity is pivotal in preserving the integrity of DNA and RNA structures, making ADA an indispensable component within the intricate network of purine metabolism essential for cellular health and functionality.